Can I Rent a Car in Mexico and Drive to Panama?

  Just received this missive from a reader: Hi.  I can’t find any useful information about the logistics of renting a car in Mexico (Cancun), and driving it south to Panama.  Is it possible?  What papers would I need (other than passport)?  Please help! I’m not in the habit of renting cars in Mexico, and I’ve never driven as far south as Panama. Anyone got anything on this?

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